Jobs
View more job listings or post a job
Jazz Pharmaceuticals Head of Toxicology
Dow Development Laboratories Formulation Chemist
Genentech Scientist, DMPK
Pliant Therapeutics, Inc. Associate Director/ Director, Formulation Development
AbVision Inc. Research Scientist (Immunology/Cell Biology, all levels available)
Regulus Therapeutics Senior Research Associate/Scientist, Drug Metabolism and Pharmacokinetics
Aligos Therapeutics Principal Research Scientist, DMPK
PPD, Inc. Senior Scientist - Quality Control - HPLC - Dissolution - Method Validation
Post a job


Position:
Research Associate, DMPK, Drug Discovery

Employer:
Maze Therapeutics

Description:

We Are Genetic Navigators bringing together passionate, creative and dedicated professionals to join a rapidly-growing startup on our mission to translate novel genetic insights into lifesaving medicines. We are integrating human genetics and functional genomics to decode the mysteries of genetic modifiers, leading us to new medicines we’ll develop for a range of severe diseases.

We are seeking a highly qualified bioanalytical Research Associate with extensive experience using LC-MS for measurement of small molecule concentrations in various matrices (i.e. blood, plasma, tissues, etc.). The ideal candidate will be familiar with various sample extraction techniques, such as liquid-liquid extraction and SPE, and should be able to perform routine LCMS method development, maintenance and troubleshooting.

Experience with high resolution mass spectrometers (Q-Exactive) and Phoenix WinNonlin software is a plus.

Your Role in Navigating The Maze:

• You will develop LC-MS methods for the analysis of small molecules.

• Prepare and analyze PK samples; process data and write PK/TK reports.

• You will perform routine LC-MS maintenance.

• You will conduct in vitro studies to determine metabolic stability, protein binding, etc.

• Coordinate with CROs for scheduling of studies and shipment of samples.



Qualifications/Experience:

Your Navigation Tools:

• BA/BS/MS in relevant field with 3+ years’ experience in DMPK within a pharmaceutical company.

• A minimum of 1 year of experience with LC-MS operation.

• Solid knowledge of PK parameters and general DMPK concepts.

• Excellent communication skills and ability to work in a team-based environment is essential.

• Experience representing DMPK in cross-functional project teams is a major plus.



Location: South San Francisco

Contact: Dan Trask - dtrask@thirdrockventures.com

Post Date: 3/1/2019 6:55:03 AM
┬ęPharmaceutical & BioScience Society, International; Last Modified: 7/19/2019; Visited: 569; Admin Logon
Ads (in random order)
Submit a Text Ad
($250 for 2 months)

Hypha Discovery mg-g scale synthesis/purification of CYP/non-CYP metabolites including glucuronides. Plus NEW PolyCYPs kits for in-house synthesis of CYP metabolites.
BIOTECH WEEK BOSTON - Sept. 9-12 Access over 5,000 of the most innovative scientific minds & business leaders in Boston and around the world. Learn More.
XCELERATE at Biotech Week Boston Driving the Future of the Life Science Industry. Sept. 11 at BCEC. Learn more.
Pacific BioLabs CRO in Bay Area - PK, toxicology, biocompatibility, analytical chemistry, immunogenicity, biomarker analysis, stability studies, sterility, endotoxin
Submit a Text Ad