Jobs
View more job listings or post a job
Chinook Therapeutics, Inc Sr. Scientist, In Vivo Pharmacology (Team Lead)
AbVision Senior/Principle Scientist (Immunology/Cell Biology)
Genentech, Inc. Associate Scientist, Biomarker Mass Spectrometry Laboratory  
Genentech, Inc. Senior Scientific Researcher for Biomarker Mass Spectrometry Laboratory
Genentech Inc. Contractor Scientist–Drug Metabolism
Genentech, Inc. Associate Scientist / Scientist, Biotransformation and ADME of New Modality  
Genentech, Inc. Scientist / Sr. Scientist, Drug Metabolism and Pharmacokinetics  
Pliant Therapeutics, Inc. Senior Research Associate, DMPK
STEMSourcing LLC DIrector Pharmacometrics
Global Blood Therapeutics SENIOR RESEARCH ASSOCIATE – DMPK
Global Blood Therapeutics SCIENTIST – DMPK
Post a job


Position:
Research Associate, DMPK, Drug Discovery

Employer:
Maze Therapeutics

Description:

We Are Genetic Navigators bringing together passionate, creative and dedicated professionals to join a rapidly-growing startup on our mission to translate novel genetic insights into lifesaving medicines. We are integrating human genetics and functional genomics to decode the mysteries of genetic modifiers, leading us to new medicines we’ll develop for a range of severe diseases.

We are seeking a highly qualified bioanalytical Research Associate with extensive experience using LC-MS for measurement of small molecule concentrations in various matrices (i.e. blood, plasma, tissues, etc.). The ideal candidate will be familiar with various sample extraction techniques, such as liquid-liquid extraction and SPE, and should be able to perform routine LCMS method development, maintenance and troubleshooting.

Experience with high resolution mass spectrometers (Q-Exactive) and Phoenix WinNonlin software is a plus.

Your Role in Navigating The Maze:

• You will develop LC-MS methods for the analysis of small molecules.

• Prepare and analyze PK samples; process data and write PK/TK reports.

• You will perform routine LC-MS maintenance.

• You will conduct in vitro studies to determine metabolic stability, protein binding, etc.

• Coordinate with CROs for scheduling of studies and shipment of samples.



Qualifications/Experience:

Your Navigation Tools:

• BA/BS/MS in relevant field with 3+ years’ experience in DMPK within a pharmaceutical company.

• A minimum of 1 year of experience with LC-MS operation.

• Solid knowledge of PK parameters and general DMPK concepts.

• Excellent communication skills and ability to work in a team-based environment is essential.

• Experience representing DMPK in cross-functional project teams is a major plus.



Location: South San Francisco

Contact: Dan Trask - dtrask@thirdrockventures.com

Post Date: 3/1/2019 6:55:03 AM
┬ęPharmaceutical & BioScience Society, International; Last Modified: 5/29/2020; Admin Logon
Ads (in random order)
Submit a Text Ad
($250 for 2 months)

Alturas Analytics, Inc. Expert GLP & non-GLP LC-MS/MS, GC-MS/MS bioanalytical & PK/TK analysis services of small & large molecules in any matrix. Discovery through phase IV.
Hypha Discovery Ltd. Experts in scalable synthesis & purification of drug metabolites, including CYP, AOX, FMO metabolites as well as O-, N-, acyl glucuronides & sulfates.
Submit a Text Ad