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Senior Research Associate to Scientist I, DMPK

ChemoCentryx Inc.


The primary responsibility of the position is to design and conduct in vitro ADME assays (e.g., CYP inhibition, metabolic stability and protein binding) and perform in vivo pharmacokinetic sample bioanalysis to support drug discovery and development. The incumbent will work closely with project teams to perform investigative DMPK studies to guide optimization of ADME properties and selection of potential drug candidates.

  • BS, MS or PhD degree in biochemistry, analytical or organic chemistry, or other relevant fields
  • For candidates with a BS or MS degree, a minimum of 3 years of experience with in vitro DMPK assays in the drug discovery or drug development environment; for candidates with a PhD, no industry experience is required
  • Hands-on experience with in vitro ADME assays including CYP inhibition, metabolic stability and protein binding is required; experience with metabolite identification is desired
  • Hands-on experience with LC/MS/MS (e.g., Sciex triple quadrupole or Thermo Q-Exactive) is required
  • Ability to troubleshoot and optimize assays as needed
  • Excellent communication skills (especially written) are required

We participate in E-Verify, the US Government sponsored right-to-work verification process.

Location: Mountain View, CA


Post Date: 3/19/2019 4:01:20 PM
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