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Bioanalytical Research Scientist, DMPK (SM/Biomarker)

Denali Therapeutics

  • Operate, maintain, and troubleshoot LC-MS/MS systems.
  • Perform bioanalysis of small molecules and biomarkers in various biological matrices including plasma, urine, CSF, and tissues of interest.
  • Develop and qualify fit-for-purpose LC-MS/MS assays.
  • Work with DMPK scientists to develop assays to support in vitro ADME studies.
  • Interpret data, write scientific reports, review and QC incoming data from CROs, and communicate bioanalysis results to other scientists and project teams.

  • PhD in Analytical Chemistry, Drug Metabolism, Pharmacokinetics, or related scientific discipline, or BS/MS with a minimum of 2 to 4 years of biotech/pharmaceutical or CRO experience.
  • Hands-on experience with various sample preparation techniques (protein precipitation, LLE, and SPE) is required.
  • Experience with chromatographic separation and mass spectrometry is highly desirable.
  • Working knowledge with GLP/GCP regulated assay is a plus.
  • Demonstrated ability to work effectively and collaboratively with other scientists on cross-functional projects teams.
  • Excellent oral presentation and written communication skills.

Location: South San Francisco

Contact: Apply on

Post Date: 9/16/2019 12:00:00 AM
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