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Research Associate, DMPK

RAPT Therapeutics

  • Conduct in vitro ADME assays, such as metabolic stability, P450 inhibition, solubility and plasma protein binding
  • Perform biological sample preparation and LC/MS-based quantitative analysis
  • Develop new assays as required
  • Help with formulation preparation as needed
  • Collect, analyze, summarize, upload to internal databases and report high quality data in a timely manner
  • Perform routine instrument maintenance; identify and troubleshoot on any issue arising while performing regular duties
  • Collaborate with team members from multiple functional areas, participate in project and PK team meetings

  • Knowledge of and experience with standard in vitro ADME/PK assays and biological sample preparation
  • In-depth experience with LCMS-based quantitative analysis (small molecules)
  • Basic understanding of ADME/PK concepts and principles
  • Strong organizational skills, flexibility, drive and attention to details
  • Ability to work with limited oversight to develop and trouble-shoot assays while delivering high quality data in a fast-paced environment
  • Excellent interpersonal skills, team spirit and demonstrated ability to work in multidisciplinary teams, interacting with members of various levels
  • Knowledge of Dotmatics and Prism a plus
  • Experience with metabolite profiling and identification desired but not required
  • Education: Bachelor's degree (B.S./B.A.) or equivalent in a scientifically related discipline with at least 2 years of industry experience
  • Ability to work in the US

Location: South San Francisco


Post Date: 10/28/2019 11:08:07 AM
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