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Position:
Senior Scientific Researcher for Biomarker Mass Spectrometry Laboratory

Employer:
Genentech, Inc.

Description:

Join a Team that Lives to Improve Lives

People come to Genentech from across disciplines and across the world to solve our most challenging medical conditions. You’ll find inspiration in our passion for biotechnology, our purpose to positively impact the lives of millions of patients and our dedication to our people. Joining Genentech means being part of a tradition of inquiry that will change the world. It means embracing our failures as much as our successes. It requires a willingness to look beyond the edge of what's possible. And a focus on doing the day-to-day work that makes great science happen. 

The following opportunity exists in our South San Francisco, CA headquarters:

 

Senior Scientific Researcher for Biomarker Mass Spectrometry Laboratory

 

Description

The OMNI-Biomarker Development department at Genentech provides translational science support to inform the clinical development of novel personalized therapeutics in disease areas of Ophthalmology, Metabolism, Neuroscience, Immunology and Infectious Diseases (OMNI). Our biomarker strategies are designed to study the molecular pathways driving the disease and to establish the mechanism of action of our therapeutics. We focus on prognostic, predictive and pharmacodynamic biomarkers to enable our vision of “the right drug for the right patient at the right dose”.



 



Qualifications/Experience:

Who You Are

As a member of the biomarker mass spectrometry laboratory, the ideal candidate will develop mass spectrometry-based assays in support of biomarker strategies, perform instrument maintenance, assist with assay transfer to external research organizations, and train others on new technology. Expertise in developing quantitative mass spectrometry assays, experience in clinical sample processing from biological matrices and a strong analytical background is required. Hands-on experience with small or large molecule sample preparation and LC and MS instrumentation is also required.

  • BS and/or MS in Analytical Chemistry, Biochemistry, or Biotechnology

  • Minimum of 5 years of hands-on experience with liquid chromatography and tandem mass spectrometry (LC-MS/MS) (SCIEX and Thermo instruments), and have strong troubleshooting capabilities

  • Strong analytical background with fundamentals in quantitative assay development and assay evaluation

  • Knowledge of sample preparation techniques for analysis of drugs, biomarkers and other mediators from biological fluids (e.g. plasma, serum, CSF, urine)

  • Demonstrated expertise in the quantitative analysis of compounds from biological matrices, especially using HPLC and HPLC-MS techniques

  • Experience developing quantitative MS techniques (e.g. SRM, MRM, or PRM). Knowledge of targeted-small molecule approaches such as developing multiplexed-MRM assays is a plus.

  • Experience with standard supportive software such as Skyline, Analyst or MultiQuant and data analytical tools such as Spotfire, R, or Prism.

  • In addition, the candidate should have excellent communication, presentation, and interpersonal skills, be able to work independently as well as in a team environment, and be willing and eager to learn new technologies.

 


A Job with Benefits Beyond the Benefits

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

At Genentech, we share salary ranges with applicants during the recruiting process, if requested. Third party salary estimates may not be accurate or up-to-date.

 



Location: South San Francisco

Contact: bit.ly/202002-103731PBSS

Post Date: 3/31/2020 3:41:44 PM
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