View more job listings or post a job
Cyprotex  Director of Business Development - We are seeking a motivated life scientist who can apply their scientific training and background in the management of existing and new business opportunities in the ADME-Tox field. 
Nektar Therapeutics Scientist II, Clinical Pharmacology
Ideaya Biosciences Inc Director, DMPK and Clinical Pharmacology
Ideaya Biosciences Inc Principal Research Scientist/Associate Director, Toxicology  
ChemoCentryx Inc. Temporary Contract Specialist– DMPK Research Associate or Scientist F
Revolution Medicines Senior Scientist, DMPK and Clinical Pharmacology
Quintara Discovery Research Scientist (Bioanalysis)
Quintara Discovery Research Scientist (Bioanalysis)
Chinook Therapeutics, Inc Sr. Scientist, In Vivo Pharmacology (Team Lead)
AbVision Senior/Principle Scientist (Immunology/Cell Biology)
Post a job

Senior Scientist, DMPK and Clinical Pharmacology

Revolution Medicines


As a Senior Scientist in DMPK and Clinical Pharmacology, you will:

  • Be a critical member of the Nonclinical Development and Clinical Pharmacology (NDCP) organization and play a key role as a functional lead in project core teams. 

  • Collaborate, align and influence cross-functional teams to identify and resolve key project questions related to DMPK and Clinical Pharmacology.

  • Design, conduct, and manage in vitro and in vivo ADME, PK and PK/PD studies in-house or at contract research organizations (CROs). 

  • Formulate strategy and oversee the design and implementation of clinical pharmacology studies. 

  • Perform human PK projection and be responsible for translational modeling to support clinical schedule optimization.

  • Draft clinical pharmacology components of protocols, investigator’s brochures and other regulatory documents.

  • Identify and manage collaboration with CROs, consultants and academic collaborators.

  • Develop high-quality protocols and maintain detailed documentation of procedure and data to comply with internal standard operating procedures and other quality criteria, where necessary.

  • A Ph.D. in Pharmaceutical Sciences, Pharmacokinetics, Drug Metabolism, or a related field with at least 5 years of relevant industry experience in supporting small molecule drug discovery and development.

  • In-depth knowledge and hands-on experience in LC/MS/MS, ADME and PK/PD study design, data analysis and interpretation.

  • Knowledge of the latest technological and regulatory advances in the field of DMPK, clinical pharmacology and modeling/simulation.

  • Experience in representing the DMPK and Clinical Pharmacology function in project teams and building strong working relationship with peers and cross-functional partners to enable high team performance.

  • Excellent written and verbal communication skills.

  • Demonstrated capability to manage and mentor junior scientists.

  • Thrives in a collaborative team setting and is driven by a desire to be innovative in a high energy, small company environment.

Location: Redwood City, CA 94063


Post Date: 6/24/2020 12:48:59 PM
┬ęPharmaceutical & BioScience Society, International; Last Modified: 8/3/2020; Admin Logon
Ads (in random order)
Submit a Text Ad
($250 for 2 months)

Alturas Analytics, Inc. Expert GLP & non-GLP LC-MS/MS, GC-MS/MS bioanalytical & PK/TK analysis services of small & large molecules in any matrix. Discovery through phase IV.
Hypha Discovery Ltd. Experts in scalable synthesis & purification of drug metabolites, including CYP, AOX, FMO metabolites as well as O-, N-, acyl glucuronides & sulfates.
Submit a Text Ad