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Scientist/Sr. Scientist -- protein/gene characterization, LC-MS

Sorrento Therapetuics



 Sorrento Therapeutics Inc. is a fast growing, clinical stage, antibody-centric, biopharmaceutical company developing new therapies to turn malignant cancers into manageable and possibly curable diseases. Sorrento's multimodal multipronged approach to fighting cancer is made possible by its' extensive immuno-oncology platforms, including key assets such as fully human antibodies ("G-MAB™ library"), clinical stage immuno-cellular therapies ("CAR-T"), intracellular targeting antibodies ("iTAbs"), antibody-drug conjugates ("ADC"), and clinical stage oncolytic virus ("Sephrevir®").

 We attract smart people who play well with others. We're small enough for your ideas to make a big impact, and large enough to offer you opportunities to grow professionally at any stage of your career.

 If you’re a quick learner, enjoy working in the biotech industry, and share our mission of providing ground-breaking impact to medicine, each other, and our patients, Sorrento Therapeutics is the place for you!


 Sorrento Therapeutics (“Sorrento”) is seeking an experienced Scientist/Sr. Scientist.  The primary responsibility of this position will be to contribute to CMC analytical method development and qualification, drug substance characterization and QC testing for therapeutic antibody, mRNA and recombinant protein. This position will design and perform experiments, interprets data and write reports, and supervises junior research associate. Work independently under minimal supervision while performing the following method development and qualification: LC-MS analysis of large molecules, SEC, IEX and RP-HPLC, Peptide Mapping, Oligonucleotide Mapping, Glycan Analysis, CIEF, and CE-SDS etc.


  • Independently plan, design, initiate and conduct experiments in support of product development and project goals.
  • Develop and validate stage appropriate analytical methods, such as HPLCs, icIEF, CE-SDS, etc. for testing of DS and DP.
  • Perform antibodies, recombinant protein, and mRNA characterization according to related ICH guidelines and develop associated analytical methods.
  • Perform QC release testing for DS and DP.
  • Demonstrate a high level of professional expertise in one or more technical areas.
  • Present results of work, interprets data, and draws conclusions regarding presented material and nature of work.
  • Author reports, protocols, test methods, and other documentation
  • Troubleshoot and maintain laboratory equipment.
  • Deliver high quality results in an accurate and a time sensitive manner.


PhD (with 0~2+ years of industrial experience) in Analytical Chemistry, Pharmaceutical Sciences, Biochemistry, or other related field of science. Work in a GMP environment a plus.


  • Support scientists who are on the leading edge of immunotherapies for the treatment of cancer. 
  • Earn a competitive salary that allows you to focus your attention on your passion.
  • A comprehensive benefits package including: medical, dental, vision, life and disability insurance, matching 401k, company paid holidays, and Flexible PTO, plus stock options.

 If this sounds like the right career to fit your personality and interests, please apply, we’re looking forward to meeting you! 

 Principals only. Recruiters, please don't contact this job poster. 

 Sorrento Therapeutics, Inc. is an Equal Opportunity Employer




PhD (with 0~2+ years of industrial experience) in Analytical Chemistry, Pharmaceutical Sciences, Biochemistry, or other related field of science. Work in a GMP environment a plus. Experience on LC-MS with large molecules  a plus.

Location: San Diego, CA


Post Date: 4/26/2021 12:00:00 AM
┬ęPharmaceutical & BioScience Society, International; Last Modified: 6/24/2021; Admin Logon
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