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Senior Scientist - ADME



Cyprotex US, an Evotec company, specializes in ADME-Tox and Biosciences including both in vitro (laboratory experiments) and in silico (computer modelling) approaches. Cyprotex was founded in 1999. The Company serves the Pharmaceutical and Biotech, Cosmetics/Personal Care and Chemicals Industries as well as academia and not-for-profit organizations. Over 1700 organizations trust Cyprotex for their ADME-Tox and Bioscience research needs.

We are seeking a Senior Scientist to be responsible for conducting routine ADME assays as well as participating in experimental design, performing experiments, troubleshooting, and performing data analysis and interpretation. This position is based on Watertown, Massachusetts.


Duties and Responsibilities

  • Perform routine in-vitro ADME assays
  • Responsible for planning, performing and reporting in vitro metabolism ADME studies for discovery and development stage compounds.
  • Actively participate in experimental design, perform experiments as well as critically analyze, interpret and report the data to design next steps.
  • Ability to perform high-impact as well as high throughput studies to completion in a fast paced environment, while managing multiple projects to meet the timelines
  • Provides scientific knowledge and responsible in establishing new ADME assays as well as contribute to the continuous improvement of the current ADME assays
  • Guide junior scientists within the department
  • Assist in data analysis and interpretation
  • Laboratory support including ordering, equipment calibration and validation Working to a high standard and adhering to our Quality System
  • Work closely with the Project Managers to ensure the requirements of our clients are met
  • Assist in running and maintaining robotic systems to support processes.
  • Perform Quality Review of peer data and assist in consolidating assay control and validation criteria
  • Work closely with the Project Managers to ensure the requirements of our clients are met



  • BS/MS in a scientific relevant field with at least 6 years of related experience in contract research organizations, pharmaceutical industries or academia. (Ph.D. preferred)
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • Industry/academic experience in DM/PK and a strong record of scientific achievement
  • Experience in drug discovery/development
  • Broad understanding of ADME, in vitro drug metabolism and DDI
  • Knowledge of bioanalytical sciences including LC-MS/MS, GC-MS, biotransformation and physical organic chemistry
  • Experienced in cell based or biochemical assays.



  • Ability to work in a team environment, remaining attentive to ideas, recognizing responsibilities, and actively participating with others to accomplish assignments and achieve desired goals.
  • Excellent oral and written communication skills
  • Knowledge and proficiency with Microsoft Word and Outlook
  • Strong attention to detail
  • Ability to communicate with peers and all levels of management
  • Ability to manage time and works independently
  • Perform other duties as assigned

Cyprotex, an Evotec company, is an Equal Opportunity Employer.  All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.

Location: Watertown, MA


Post Date: 7/8/2021 7:49:54 AM
┬ęPharmaceutical & BioScience Society, International; Last Modified: 10/26/2021; Admin Logon
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