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Position:
Associate Scientist - Antibody Engineering 

Employer:
Peak Bio

Description:

Peak Bio is a newly created venture out of the San Francisco Bay Area that will soon reach a critical milestone in our history of going public on NASDAQ. We are seeking scientific and business talent at two of our critical sites that include our center of research excellence in Palo Alto, California and our G&A infrastructure in South Florida.

Peak Bio is a clinical-stage biopharmaceutical company focused on commercializing innovative therapeutics that aim to improve and address significant unmet medical needs for patients with inflammatory, rare and specialty diseases and cancer. We seek qualified, energetic, and talented individuals with a desire for growth, and advancement but with a knack for working in a cross-cultural, team-based environment. The talent we seek works well with others and knows that, in the end, the company’s overarching goal is to improve the human health experience and help solve the medical mysteries that challenge us daily. As a company we will continue to explore, work closely with and partner with external researchers, clinicians, patient advocacy groups, academic institutions, governmental agencies, and our investors to continue to expand treatment options and partnerships to meet those expectations and find novel approaches to treat disease.

This is a full-time position based in our Palo Alto, California offices, and will initially report to the Head of Oncology.

This role will be critical in driving the future of our business, demonstrating the ability to work scientifically with a unique business model, working collaboratively amongst other talented scientists who utilize expertise, analytics, creativity and ingenuity to succeed, and applying advanced knowledge in antibody engineering.

 Key Responsibilities

  • Contribute to the identification of new therapeutic targets
  • Implement new advances in antibody generation and recovery
  • Design and engineer antibodies, bi-specifics and Fc proteins
  • Establish in-house antibody design and generation capabilities
  • Establish creative and efficient molecular cloning of antibody variable genes
  • Perform molecular biology support functions such as DNA isolation, primer design, PCR, DNA preps and purifications
  • Perform antibody sequence analysis
  • Develop ELISAs for the detection of antibodies in culture supernatants, as well as ADC conjugations and analyzed conjugates by chromatography
  • Present analytical analysis of for protein purity (size exclusion and reverse phase HPLC, isoelectric focusing, HIC)
  • Manage database functions


Qualifications/Experience:

Desired Abilities and Qualifications

  • A Ph.D. in Molecular Biology, Protein Engineering or related sciences.
  • 1-5 years of industry experience, with advanced knowledge of antibody structure and function
  • Working operational knowledge of standard equipment and software for protein and cell biology
  • Molecular biology and recombinant DNA cloning skills
  • Working knowledge of cell based assays and flow cytometry assays
  • Excellent communication skills to cross functional teams
  • Meticulous record keeping skills
  • Ability to prioritize, particularly under tight deadlines
  • Can succeed independently or as part of a collaborative team
  • Experience with Biacore/ Octet, antibody drug conjugation, bispecific antibodies, and/or antibody discovery using single B-cell technology are all preferred

 What you will enjoy while working with us

(Any or all of these benefits are subject to change at any time at Peak Bio’s discretion).

  • Competitive Pay
  • Bonus Eligibility
  • Stock Option Eligibility
  • Health Care Plan
  • Medical
  • Dental
  • Vision
  • 401(k) Plan
  • Family Leave (Maternity, Paternity)
  • Life Insurance
  • Long- and Short-Term Disability
  • Generous PTO Policy
  • Paid Company Holidays

 Does Peak Bio’s mission and unique business model ignite your passion and interest? Does the opportunity to work alongside talented and welcoming team members make you want to join? Do the responsibilities and qualifications translate very similarly to what you have to offer? Does the overall benefits package make you feel valued and appreciated? If you answer “yes” to these questions, we definitely want you to apply.

Job candidates should be aware that full vaccination against COVID-19 is required as a condition of employment subject to legally required exceptions. Peak Bio is an equal opportunity employer and encourages potential or current employees to request a reasonable accommodation under federal, state and local regulations, should one be needed.

 

Please apply using the following link: https://peakbio.bamboohr.com/jobs/view.php?id=56&source=aWQ9MTE%3D

 

 

 



Location: Palo Alto, CA

Contact: Maja: 408-781-7387

Post Date: 8/29/2022 12:00:00 AM
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